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Sara Tolaney· @stolaney1 · X·· 2 days agoScore90

HER2

Body

NSABP B-42:
n=3966
median f/u 15.9 yrs
57% node-neg, 78% HER2-
39% prior tamoxifen
15 yr BCFI: HR 0.78
Distant Recurrence: HR 0.72
N-: HR0.78, N+ HR 0.69
OS HR 0.92

@OncoAlert #ESMO26

807 views · 16 likes · 12 reposts · 0 replies

Conference abstracts
1766ROmatched by Rapid oral 1: Breast cancer, advanced stage

Health-related quality of life from HER2CLIMB-05: A phase 3 study of tucatinib versus placebo in combination with trastuzumab and pertuzumab as 1L maintenance therapy for HER2+ mBC

https://esmocongress.esmo.org
1780Pmatched by HER2+ breast cancer

Safety, social costs and quality of life (QOL) in HER2-positive (HER2+) breast cancer (BC) patients (pts) treated with pertuzumab + trastuzumab fixed-dose combination subcutaneous (PT FDC SC): The PERTURB study

https://esmocongress.esmo.org
1795TIPmatched by HER2+ breast cancer

A global, interventional, open-label trial of trastuzumab deruxtecan (T-DXd)–based therapy in first-line HER2-positive metastatic breast cancer: DESTINY-Breast Guide

https://esmocongress.esmo.org
1842Omatched by Proffered paper 2: Breast cancer, early and advanced stage

Efficacy and safety of atirmociclib (ATI) + fulvestrant (FUL) in patients (pts) with HR+/HER2– advanced/metastatic breast cancer (mBC) who progressed on prior CDK4/6 inhibitor (CDK4/6i) in a randomized phase 2 study (FOURLIGHT-1)

https://esmocongress.esmo.org
1844Pmatched by HR+ breast cancer

Gene-expression profiling of HR+/HER2- breast cancers arising in germline BRCA1/2 mutation carriers

https://esmocongress.esmo.org

Source: Sara Tolaney · x.com

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