medicalxpress.com· Medical Xpress - Cancer·· 19 hours agoPickScore68
How blocking immune cell signals could make brain tumors easier to remove
In brief
A VIB-KU Leuven research team reports in Cancer Cell that LPAs released by microglia promote invasion of healthy brain tissue by glioblastoma cells. Blocking this signal reduced invasiveness but did not shrink the tumor.
Why it matters
The study links microglia-released lipid signaling to glioblastoma invasion and reproduces it in patient samples and cell lines, suggesting a pre-surgical way to limit tumor spread.
Source: medicalxpress.com · medicalxpress.com