🚨 Negative results from KEYNOTE-866 at #ESMO26.

Juan Pablo Rojas Manrique· @JPRojasUroOnco · X·2026-10-23 19:44· 2 days agoScore70

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Perioperative pembrolizumab added to neoadjuvant gemcitabine/cisplatin failed to significantly improve event-free survival in muscle-invasive bladder cancer (HR 0.88; 95% CI 0.71–1.10; P=0.1366).

#BladderCancer

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Conference abstracts

4735Omatched by Proffered paper 1: Genitourinary tumour, renal and urothelial

Perioperative pembrolizumab (pembro) or placebo (pbo) + neoadjuvant cisplatin (cis) and gemcitabine (gem) in participants (pts) with muscle-invasive bladder cancer (MIBC): the double-blind, phase 3 KEYNOTE-866 study

https://esmocongress.esmo.org

Source: Juan Pablo Rojas Manrique · x.com