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Oriol Mirallas MD· @DrMirallas · X·· 15 hours agoScore70

INTERPATH-001

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🔥 Presidential Symposium I #ESMO26

INTerpath-001: double-blind phase 3 study of intismeran (mRNA vaccine) + pembro as adjuvant therapy for resected stage IIB–IV #melanoma

✔️ RFS 82.2 vs 70% HR 0.58
✔️ DMFS 88.5 vs 80.2% HR 0.62
☣️ No increased risk of toxicity in the combination

✅🧫 mRNA Vaccine in adjuvant melanoma treatment together with anti-PD1

@OncoAlert @myESMO @ASCO @_SEOM @UTMDAnderson @brunolarvol
👇🏽👇🏽

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Conference abstracts
LBA1matched by Presidential Symposium I

INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)

https://esmocongress.esmo.org

Source: Oriol Mirallas MD · x.com

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