nature.com·· 16 hours agoPickScore56
Recordanelles capture transient gene expression in single human cells
Recordanelles capture transient gene expression in single human cells
In brief
The synthetic organelle recordanelle can record RNA in single human cells for several days and be read with single-cell sensitivity. RNA sequencing captures high-resolution snapshots of the transcriptome but cannot capture transient changes in individual cells over longer periods at a transcriptome-wide scale. doi:10.1038/s41587-026-03350-7.
Why it matters
Recordanelles record cellular RNA for several days and read at single-cell sensitivity, addressing RNA sequencing's inability to capture transient single-cell changes over time.
Source: nature.com · nature.com