Important #ESMO26 study, published in @Annals_Oncology !
In the phase 3 PERSEE trial adding chemotherapy to pembrolizumab in advanced lung cancer with PD-L1 ≥50% improved median progression-free survival from 6.9 to 16.1 months (HR 0.56).
Median overall survival was 50.2 vs 29.9 months (HR 0.77), although the difference was not statistically significant.
Grade ≥3 treatment-related adverse events increased (54% vs 19%).
An important finding for first-line treatment decisions in PD-L1-high lung cancer.
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https://esmocongress.esmo.org- ilyas sahin, MD@ilyassahinMD
https://www.annalsofoncology.org/article/S0923-7534(26)06892-4/fulltext
Source: ilyas sahin, MD · x.com