bioRxiv Genomics· Liu, H., Kim, J. J. ·· 20 hours agoPickScore61
ONT-LibQC: rapid quality control of chromatin assay libraries using shallow nanopore sequencing
In brief
ONT-LibQC uses roughly 3,000 shallow ONT sequencing reads to reconstruct finished CUT&RUN or Micro-C library molecules before deep Illumina sequencing, identify adapters and indexes, and assess fragment sizes and biological signal enrichment.
Why it matters
ONT-LibQC uses a few thousand shallow ONT reads to report signal enrichment and fragment structure of CUT&RUN and Micro-C libraries before deep Illumina sequencing.
Source: bioRxiv Genomics · biorxiv.org