Clinical trials mini symposium #AACR26

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Oriol Mirallas MD· @DrMirallas · X·2026-04-19 02:12· 2026-04-19Score60

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Clinical trials mini symposium #AACR26

Dr. Garralda
@VHIO

DKY709: IKFZ2 degrader +/- PS1 in pretreated #ICI
@Novartis

3PR and 1CR
1CR beyond 2.5y
DVR 41%
Most common: ALT, rash and diarrhea, 2DLT in comb
Peripheral neuropathy + QTc

@AACR

@OncoAlert

Heat 8 · 5 likes · 1 reply · 2 reposts

Conference abstracts

CT006NCT03891953matched by 代号 DKY709

Phase 1 DKY709A12101C study in patients with advanced solid tumors treated with DKY709, an IKZF2 degrader, alone or in combination with PDR001, a PD-1 inhibitor

Elena Garralda, Chia-Chi Lin, Takafumi Koyama, Brigette Ma, Melissa Johnson, Martin Schuler, Martin Wermke, Justin Gainor, Raj Gopal, Debby Long, Jaeyeon Kim, Divyasree Maddirala, Anhthu Dang, Xin Yang, Mark Awad

Read the abstract →

Source: Oriol Mirallas MD · x.com