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Yuhei YAMAGUCHI· @yymgcmd · X·· 1 day agoScore45

PIK3CA

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CDK4 inhibitors will likely enter routine breast cancer care.
🧐For 2nd-line endocrine therapy, biomarker-guided treatment based on ESR1, PIK3CA/AKT1/PTEN alterations or CDK4 inhibition?
💡One advantage of CDK4 inhibitors: no CDx required.
#ESMO26

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Very promising randomized results with the CDK4 selective inhibitor atirmociclib presented by @antgiorda. Next gen CDKs are here! #ESMO26 #ESMOAmbassadors
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Source: Yuhei YAMAGUCHI · x.com

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