J Cell Biol· The Journal of cell biology·· 2 days agoPickScore67
Adhesion integrity activates mechanosensitive proliferative signaling
In brief
A study in the Journal of Cell Biology suggests that intact cell adhesion can give premalignant cells a proliferative advantage before adhesion weakens, via Src-associated mechanosensitive signaling.
Why it matters
Links adhesion integrity to Src-associated proliferative signaling; P-cadherin and FAK may give premalignant cells a proliferative edge before adhesion weakens.
Source: J Cell Biol · pubmed.ncbi.nlm.nih.gov