WeChat· 药通社·· 4 hours agoPickScore76
FDA Approves GSK's Bepirovirsen Combined with NrtIs for Chronic Hepatitis B
In brief
GSK announced that its antisense oligonucleotide drug Bepirovirsen has received FDA approval, in combination with nucleos(t)ide reverse transcriptase inhibitors (NrtIs), for chronic hepatitis B virus infection. According to the source, the drug was previously approved in Japan and is the world's first approved functional cure therapy for chronic hepatitis B, defined as undetectable HBV DNA and HBsAg in blood for 24 weeks or longer after stopping treatment.
Why it matters
Source gives the approved indication and use of Bepirovirsen with NrtIs, useful reference for similar ASO programs.
Source: WeChat · mp.weixin.qq.com