JAMA·· 14 hours agoPickScore66
A Common CD36 Variant and the Genetic Landscape of Dilated Cardiomyopathy in Individuals of African Ancestry.
In brief
In a multicohort genetic association analysis of 82,623 individuals of African ancestry, the population attributable fraction of dilated cardiomyopathy for CD36 Y325* was 9.0%, higher than the 3.7% for TTN truncating variants.
Why it matters
CD36 Y325* shows a PAF of 9.0% versus 3.7% for TTN truncating variants, informing evaluation of DCM genetic screening targets in this population.
Source: JAMA