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UT MD Anderson· @UTMDAnderson · X·· 17 hours agoScore70

durvalumab

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Phase 3 DUO-E results show that adding durvalumab and olaparib to treatment extended median overall survival by 11.5 months for patients with advanced or recurrent endometrial cancer compared with chemotherapy alone.

Presented by Dr. Shannon Westin at #ESMO26, the findings are especially encouraging for patients with pMMR tumors.

Read more: http://spr.ly/6017BHj4xf @ShannonWestin #EndCancer

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Conference abstracts
2879ROmatched by Rapid oral 1: Gastrointestinal tumour, upper digestive

Durvalumab plus definitive chemoradiotherapy versus definitive chemoradiotherapy in patients with locally advanced esophagus carcinoma: ARION PRODIGE 67 randomized phase 2 trial

https://esmocongress.esmo.org
4737ROmatched by Rapid oral 1: Genitourinary tumours, renal and urothelial

Durvalumab (D) in Combination With BCG Induction and Maintenance (I+M) for BCG-Naïve, High-Risk Non-Muscle-Invasive Bladder Cancer (NMIBC): Early Recurrence and Cystectomy-Free Survival in Patients (pts) With Papillary Only Tumours From POT

https://esmocongress.esmo.org
LBA2matched by Presidential Symposium I

Perioperative durvalumab with or without tremelimumab plus neoadjuvant enfortumab vedotin in muscle-invasive bladder cancer: Results from the phase 3 VOLGA trial

https://esmocongress.esmo.org
LBA26matched by Proffered paper 2: Breast cancer, early and advanced stage

Short-term preoperative durvalumab for stage I TNBC: First results from the phase II UNLOCK 14 - POP-DURVA trial

https://esmocongress.esmo.org
LBA3matched by Presidential Symposium I

Tarlatamab plus durvalumab (durva) vs durva as 1L maintenance (1LM) therapy following durva, platinum, and etoposide (1L durva + EP) in extensive-stage small cell lung cancer (ES-SCLC): Primary analysis of the phase 3 DeLLphi-305 trial

https://esmocongress.esmo.org
LBA37matched by Proffered paper: Gynaecological cancers

Durvalumab (D) plus carboplatin/paclitaxel (CP) followed by D with or without olaparib (O) in advanced/recurrent endometrial cancer (a/rEC): Interim overall survival (OS) and safety from the randomised phase 3 DUO-E/GOG-3041/ENGOT-EN10 stud

https://esmocongress.esmo.org

Source: UT MD Anderson · x.com

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