Science· Jacob Helm, Elena Buena-Atienza, Clemens M. Sauter, Linus Wiora, Melanie Kraft, Yvonne Schelling, Jakob Admard, Jeannette Hübener-Schmid, Thomas Klockgether, Matthis Synofzik, Luís Pereira de Almeida, Mafalda Raposo, Paola Giunti, Hector Garcia-Moreno, Magda M. Santana, Jennifer Faber, Holger Hengel, Nicolas Casadei, Ludger Schöls, Stefan Hauser·· 17 hours agoScore62
Single-nucleotide polymorphism–directed design of allele-specific antisense oligonucleotides for spinocerebellar ataxia type 3
In brief
This study uses single-nucleotide polymorphisms to guide the design of allele-specific antisense oligonucleotides for spinocerebellar ataxia type 3. The article appears in Science Translational Medicine, Volume 18, Issue 872 (October 2026), DOI 10.1126/scitranslmed.adz2140. The available material provides only the title and volume information; experimental design, data, and conclusions are not disclosed.
Source: Science