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Dr Amol Akhade· @SuyogCancer · X·· 2 days agoScore70

SANO

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With increase in distant mets , will you offer wait and watch in Esophageal cancer? I won't. #SANO trial. @myESMO #esmo26 @OncoAlert

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Conference abstracts
LBA78matched by Proffered paper 1: Gastrointestinal tumour, upper digestive

Active surveillance versus standard surgery after neoadjuvant chemoradiotherapy for oesophageal cancer: Long-term results of a cluster-randomised controlled trial (SANO)

https://esmocongress.esmo.org
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🚨 ESMO 2026 | SANO Trial (LBA78): 5-Year Result Active surveillance vs surgery (N=309) 🔹 5-year OS: 50% vs 54% (HR 1.17; 95% CI 0.77–1.77) 🔹 DFS: HR 1.39 (95% CI 0.94–2.06) 🔹 5-year distant metastases: 46% vs 29% (p<0.01) 🔹 43% in the surveillance arm were spared a non-beneficial oesophagectomy. An important organ-preservation strategy, but the higher distant metastasis rate is concerning. Would you recommend active surveillance over surgery for a patient achieving complete clinical response? #ESMO26 #EsophagealCancer #SANO @myESMO @NiuSanford @OncoAlert @OncBrothers
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  1. Lucas Ferreira@drlucaslf

    @SuyogCancer @myESMO @OncoAlert No Way!

Source: Dr Amol Akhade · x.com

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