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AACR 2026 现场信号· @ · X·· 2026-04-22Score60

#EOCRC

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KRAS / RAS 靶向 — 从平台化到 Ph3 验证

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🧠 New insight from Dr. @AndrewChanLab’s plenary session at #AACR26: How does past inflammation trigger future cancer risk? It’s all about Epigenetic Memory. 🧬

Even after tissue "recovers" from inflammation, cells don't fully reset. They retain a "latent memory" encoded in their chromatin structure. 📜

When the tissue is triggered again, this "primed" state leads to an augmented, aggressive response that can accelerate tumor growth. Understanding and reversing this "memory state" is a major target for preventing #EOCRC! 🛡️✨
@AmericanCancer @SU2C @AACR @OncoAlert @MassGeneralNews @HarvardChanSPH

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Source: AACR 2026 现场信号 · x.com

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