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Targeted Oncology· @TargetedOnc · X·· 15 hours agoScore70

DELLPHI-305

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Remarkable OS benefit in ES-SCLC! #ESMO26

DeLLphi-305: Tarlatamab + durvalumab maintenance vs durvalumab:

Median OS: 21.1 vs 12.7 mo (HR 0.42)
PFS: 7.4 vs 1.9 mo (HR 0.34)

An 8.4-month difference in median survival. Potentially practice-changing!

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Conference abstracts
LBA3matched by Presidential Symposium I

Tarlatamab plus durvalumab (durva) vs durva as 1L maintenance (1LM) therapy following durva, platinum, and etoposide (1L durva + EP) in extensive-stage small cell lung cancer (ES-SCLC): Primary analysis of the phase 3 DeLLphi-305 trial

https://esmocongress.esmo.org

Source: Targeted Oncology · x.com

CBACBA Frontier Insights (CFI)Chinese Biopharmaceutical Association (CBA)www.cba-usa.org