YouTube· KeystoneSymposia · YouTube·· 14 hours agoScore42
Nucleic Acid Drug Delivery: A Keystone Joint Meeting Overview with Davidson and Bennett
In brief
Beverly Davidson (CHOP/Penn) and Frank Bennett (Ionis) discuss delivery of nucleic acid drugs such as ASOs and siRNAs to different organs at a Keystone joint meeting, noting that delivery modalities are expanding explosively rather than replacing existing approaches. Held jointly with the Precision Genome Engineering meeting, it focuses on combining these delivery methods with precision engineering in patients carrying specific mutations. The content is a meeting overview tracing the technical spectrum and translational path of nucleic acid delivery from early development to early human use.
Key points
Beverly Davidson (CHOP/Penn) and Frank Bennett (Ionis) introduce Keystone.
- Core question: how to deliver nucleic acids (ASOs/siRNAs, etc.) to different organs to create drugs that impact patients' lives.
- Viewpoint: the toolbox is 'expanding' rather than replacing old methods—delivery modalities have grown explosively from just a few; the conference aims to show academia/industry the diversity from early development to early human applications.
- Co-held with the 'Precision Genome Engineering' conference: the delivery methods discussed will be used for patients carrying specific mutations, combined with precision engineering.
- Positioning: a conference overview/conversation, not a single research report; its value lies in mapping the technical landscape and translational pathway of nucleic acid drug delivery.
Source: YouTube