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がんナビ通信· @cancer_navi · X·· 2026-04-19Score60

zanidatamab

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ADC 下一代 — 载荷创新

zanidatamab 新辅助 · 无化疗 pCR 30%,HER2 下调 56%

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This is a breaking report from AACR, one of the world's largest cancer research conferences. The anti-HER2 bispecific antibody zanidatamab has been reported, based on results from the phase 2 NeoZanHER trial, to potentially be effective as neoadjuvant therapy for HER2-positive

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Conference abstracts
CT012matched by 药名 zanidatamab
A phase 2 single-arm open-label trial evaluating zanidatamab in patients with early stage HER2 positive breast cancer: The NeoZanHER Study

Vicente Valero, Paula R. Pohlmann, Jason Mouabbi, Xuelin Huang, Wei Qiao, Heather R. Alonzo, Rashmi Krishna Murthy, Gaiane M. Rauch, Taiwo Adesoye, Cristina M. Checka, William F. Symmans, Dmitri Grachev, Flora Alajajyan, Adaeze Nwosu-Iheme, Amy Hassan, Miral Mahesh Patel, Sharon H. Giordano, Kelly Hunt, Debasish Tripathy, Funda Meric-Bernstam

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Source: がんナビ通信 · x.com

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