KRAS / RAS targeting: from platform to Phase 3
The floor also showed dual ON/OFF (VS-7375) and RM-055, built for amplification and daraxonrasib-resistant models.
The floor rewrote the question from “how long can G12C monotherapy last” to “who first makes first-line pancreatic cancer a standard.” daraxonrasib’s Phase 3 is still the only RAS-inhibitor overall-survival win.
📣 #AACR26 HIGHLIGHTS 📌 The new episode of #TooMoreGi by @DrAngelaLamarca is now available!
👉 @DrAngelaLamarca presents the latest updates from #AACR26 in pancreatic cancer, featuring highly promising new data from two first-line studies in mKRAS, highlighting high response rates and very meaningful disease control in both trials.
✔ #Daraxonrasib monotherapy in 1L #mKRAS #PDAC
✔ #Daraxonrasib + GemNab-paclitaxel in 1L #mKRAS #PDAC
And also… 🚨 Road to #ASCO26: daraxonrasib shows an overall survival benefit in 2L vs chemotherapy (RASOLUTE-302)
🎧 Press play and find out: https://t.co/3YyYDHBCFg
#Oncology #AACR26 #MedicalEducation
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