‼️ Impressive results from DeLLphi-305 (phase III) just out this afternoon #ESMO26.
Tarlatamab + durvalumab vs durvalumab alone, 1L maintenance ES-SCLC. Median OS 21.1 vs 12.7 months, HR 0.42, 58% reduction in risk of death.
This is great news for people affected by small cell #lungcancer. Both drugs already have EU and UK approvals on their own.
The real gap: new medicines can still take 600+ days to reach patients in lower-income European countries. Practice-changing data is only half the story.
https://lungcancereurope.eu/news/tarlatamab-durvalumab-dellphi-305-sclc-survival #LCSM
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Tarlatamab plus durvalumab (durva) vs durva as 1L maintenance (1LM) therapy following durva, platinum, and etoposide (1L durva + EP) in extensive-stage small cell lung cancer (ES-SCLC): Primary analysis of the phase 3 DeLLphi-305 trial
https://esmocongress.esmo.orgSource: Lung Cancer Europe · x.com