文献与产业新闻· Proceedings of the National Academy of Sciences of the United States of America·· 2026-08-31PickScore58
Interpreting vaccine-associated survival differences in immune checkpoint inhibitor therapy
In brief
Karadakic, Barnett and colleagues used 100% US Medicare fee-for-service claims data to compare survival associations after mRNA COVID-19, adenoviral COVID-19, and influenza vaccination before versus after ICI initiation, among 121,676 beneficiaries starting systemic anticancer therapy, including 10,824 ICI users.
Why it matters
The study compares mRNA COVID-19, adenoviral COVID-19, and influenza vaccines in parallel in the same dataset, a key control for isolating mRNA-specific effects.
Source: 文献与产业新闻