ctDNA + genomics finally refining perioperative IO in resectable NSCLC 👀
Same topic KEAP1 · 3 peopleSTK11SMARCA4#ONCOTWITTER#LUNGCANCER#NSCLC#CTDNA#PRECISIONONCOLOGY#THORACICONCOLOGYHeat 3524 likes0 replies11 reposts
AACR Annual Meeting 2026
April 17–22, 2026 · San Diego · 2418 items
← KRAS / RAS targeting: from platform to Phase 3
KEAP1
3 people · 3 posts
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Heat now 0·Peak in the comparable set 1 (Apr 22 06:00)·Change over 24h in the comparable set –·Participants now 1
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Other cases in this chapter
- daraxonrasibmOS 13.2 vs 6.7 mo, HR 0.40
- daraxonrasib ± GnPmono ORR 47%; +GnP ORR 55%, DCR 90%
- zoldonrasibORR 52%, DCR 93%, mPFS 11.1 mo; ctDNA clearance 73%
- VS-7375NSCLC ORR 68.8% (n=16); pancreas ORR 58%
- elisrasibG12Ci-naive NSCLC ORR 59.5%; pretreated 32.3%
- RM-055Active in daraxonrasib-resistant and RAS-amplification models
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Stephen V Liu, MD@StephenVLiuScore6060