🚨 #ESMO26 Lung Cancer: Top Ten by @OncoAlert 🫁 The abstracts our faculty picked as must-know from Madrid 👇 1️⃣ DeLLphi-305 (LBA3): tarlatamab + durvalumab, 1L maintenance in ES-SCLC 2️⃣ Krascendo 1 (LBA5): divarasib vs sotorasib/adagrasib in KRAS G12C NSCLC 3️⃣ SAFFRON (LBA6): osimertinib + savolitinib in EGFRm MET+ NSCLC post-osimertinib 4️⃣ OptiTROP-Lung04 (LBA67): final OS, sac-TMT vs chemo after EGFR-TKI 5️⃣ OptiTROP-Lung06 (LBA66): sac-TMT + pembro, 1L PD-L1-negative non-squamous NSCLC 6️⃣ PERSEE (2614O): pembro ± chemo, 1L PD-L1 ≥50% 7️⃣ SANOVO (LBA69): savolitinib + osimertinib, 1L EGFRm MET-overexpressed NSCLC 8️⃣ IFCT-2103 DIAL (2618RO): continue pembro vs observation at 6 months 9️⃣ PANKU-Lung01 (LBA71): iza-bren after third-generation EGFR TKI 🔟 SARON (2613O): consolidation radiotherapy in oligometastatic NSCLC #lcsm #OncoAlert #MedTwitter Pinging our OncoAlert Lung Cancer Faculty @christine_lovly, @GlopesMd, @DrSanjayPopat, @StephenVLiu, @jillfeldman4, @UOzkerim, @DrMirallas, @MartinReck2 , @bmassutis @UmbertoMalapel1 , @CharuAggarwalMD @peters_solange, @HenningWillers, @HHorinouchi, @BRicciutiMD, @PercyLeeMD, @bensolomon1, @Latinamd, @DrJNaidoo, @barlesi, @VanitaNoronha, @ChristianRolfo @Tony_Calles @s_couraud @marinagarassino @g_mountzios @BairdAM @barlesi @JFreemanDaily @Piuchagarrido @LeciaSequist @bensolomon1 @VanitaNoronha +@alexdrilon @JordiRemon @caliraf @JulienMazieres @TerriConneran

AACR 2026 年会
2026 年 4 月 17–22 日 · San Diego · 共 2429 条
#LCSM
2 人 · 2 条
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- adebrelimab围手术期 EFS HR 0.52
- taletrectinibROS1+ ORR 90%,DoR 49.7 月
- CheckMate 77TctDNA 清除者才有高 pCR
- LCINS / Sherlock-Lung1209 例 WGS:不吸烟 EGFR、吸烟 KRAS
gilberto lopes@GlopesMd 引用@Hidehito HORINOUCHI@HHorinouchi Víctor Albarrán-Artahona@vmalbarran Hidehito HORINOUCHI@HHorinouchi Hidehito HORINOUCHI@HHorinouchi Hidehito HORINOUCHI@HHorinouchi Hidehito HORINOUCHI@HHorinouchi Dr. Antonio Calles 🫁🚭@Tony_Calles 🧬 @LeXiuning 全面探讨了 ctDNA 动态变化以及 EGFRmut 肺癌患者的适应性强化治疗方案。 核心结论:联合治疗方案是一线治疗的默认选择。 #ESMO26 #LCSM
Hidehito HORINOUCHI@HHorinouchi 引用@Delighted to join Dr Yi-Chen Zhang, Dr Calvo de Juan and Prof Yi-Long Wu in discussing the role of local therapy in non-small cell lung cancer at #ESMO26 in #Madrid this afternoon. Superb case discussion and fascinating insights into novel approaches such as the role of ctDNA In selection and monitoring of patients. @myESMO @CancerInstIRE @tcddublin @TrinityMed1
VJ Oncology@VJOncology Prof Tom John@TommyJohn00 Hidehito HORINOUCHI@HHorinouchi Lung Cancers Today@Lung_Cancers Hidehito HORINOUCHI@HHorinouchi Lung Cancers Today@Lung_Cancers OncLive.com@OncLive 您最期待在 2026 年 ESMO 大会上看到哪篇肺癌摘要? @myESMO #ESMO2026 #lcsm #oncology
LUNGevity Foundation@LUNGevity Dr. Antonio Calles 🫁🚭@Tony_Calles 你真当之无愧!❤️ #ESMO26 有你在,#LCSM 社群好多了!!!继续加油,朋友!!💪
引用@It was an amazing surprise! Gracias Totales! #ESMO26
OncLive.com@OncLive VJ Oncology@VJOncology Tom Newsom-Davis@tnewsomdavis VJ Oncology@VJOncology Hidehito HORINOUCHI@HHorinouchi 引用@Delighted to join Dr Yi-Chen Zhang, Dr Calvo de Juan and Prof Yi-Long Wu in discussing the role of local therapy in non-small cell lung cancer at #ESMO26 in #Madrid this afternoon. Superb case discussion and fascinating insights into novel approaches such as the role of ctDNA In selection and monitoring of patients. @myESMO @CancerInstIRE @tcddublin @TrinityMed1
Hidehito HORINOUCHI@HHorinouchi 引用@Delighted to join Dr Yi-Chen Zhang, Dr Calvo de Juan and Prof Yi-Long Wu in discussing the role of local therapy in non-small cell lung cancer at #ESMO26 in #Madrid this afternoon. Superb case discussion and fascinating insights into novel approaches such as the role of ctDNA In selection and monitoring of patients. @myESMO @CancerInstIRE @tcddublin @TrinityMed1
Prof Tom John@TommyJohn00 Prof Tom John@TommyJohn00 PACE lung:ctDNA 未清除者的治疗升级。希望能进一步了解 ctDNA 阳性组的共突变情况。#LCSM #ESMO26
Lung Cancers Today@Lung_Cancers MeDucation@MeDucationai 引用@Important implications for lung cancer, too. We’re behind breast cancer in understanding optimal ADC sequencing, but emerging data raise an important concern: switching targets may not overcome resistance when the payload remains the same... #ESMO26