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Melatonin and Ambien before surgery may improve sleep, reduce pain and opioid use after surgery

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A pooled analysis of 25 years of research suggests that preoperative melatonin or Ambien (zolpidem) may improve patient sleep, ease presurgical anxiety, reduce postoperative pain and lower opioid requirements, aiding recovery after surgery. The findings were presented at the ANESTHESIOLOGY 2026 annual meeting.

Excerpted from Medical Xpress

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Oct 19
  1. Medical XpressPick
    Melatonin and Ambien before surgery may improve sleep, reduce pain and opioid use after surgery

    A pooled analysis of 25 years of research suggests that preoperative melatonin or Ambien (zolpidem) may improve patient sleep, ease presurgical anxiety, reduce postoperative pain and lower opioid requirements, aiding recovery after surgery. The findings were presented at the ANESTHESIOLOGY 2026 annual meeting.

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