Osmosis Explains Biliary Atresia: Types, Clinical Features, Diagnosis and Treatment
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Biliary atresia is a disease in which extrahepatic bile duct obstruction causes cholestasis, progressive fibrosis and eventually cirrhosis. It has a fetal form, associated with congenital anomalies, and a perinatal form with onset at 2 to 6 weeks of age. Findings include elevated conjugated bilirubin, progressive jaundice, acholic stools and failure to thrive; diagnosis relies on laboratory tests and imaging. The main treatment is the Kasai portoenterostomy, with liver transplantation needed in late-stage disease.
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- YouTubeOsmosis Explains Biliary Atresia: Types, Clinical Features, Diagnosis and Treatment
Biliary atresia is a disease in which extrahepatic bile duct obstruction causes cholestasis, progressive fibrosis and eventually cirrhosis. It has a fetal form, associated with congenital anomalies, and a perinatal form with onset at 2 to 6 weeks of age. Findings include elevated conjugated bilirubin, progressive jaundice, acholic stools and failure to thrive; diagnosis relies on laboratory tests and imaging. The main treatment is the Kasai portoenterostomy, with liver transplantation needed in late-stage disease.
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