Jon Kagan maps how innate immunity senses infection and tissue damage

Jon Kagan gives a 57-minute Global ImmunoTalks lecture on how the innate immune system recognizes infection and tissue damage, centred on inflammasome pathways driven by Toll-like receptors, NOD-like receptors, RIG-I-like receptors, caspases and STING. He describes building a map of innate immune signalling sites at cellular and subcellular scale, pathways central to anti-infection and anti-tumour immunity. Kagan is co-founder of co-therapeutics and advises several immunotherapy companies.