Crick Institute speaker explains interferon's dual role in lung infections

A 58-minute expert talk from Global ImmunoTalks features a researcher from the Francis Crick Institute who studies host determinants of respiratory infection severity, focusing on interferon and inflammation, lung epithelial and endothelial biology, and type I/II interferons in immunopathology and tissue repair. The speaker argues interferon is not simply protective in lung infection: it can also drive immune pathology and tissue damage, and acute infection can have long-term effects on lung immunity. Host factors, not antiviral responses alone, determine heterogeneous infection outcomes.