Translating base editors: a decade of progress from the bench to the clinic
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A review in Nature Reviews Drug Discovery marks ten years since base editing, a gene editing technology that installs point mutations with high efficiency and precision, was first reported. It traces the evolution of base editors and their path to clinical translation, covering key advances and remaining challenges. It also surveys the current clinical trial landscape for the technology.
Excerpted from nature.com
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- nature.comPickTranslating base editors: a decade of progress from the bench to the clinic
A review in Nature Reviews Drug Discovery marks ten years since base editing, a gene editing technology that installs point mutations with high efficiency and precision, was first reported. It traces the evolution of base editors and their path to clinical translation, covering key advances and remaining challenges. It also surveys the current clinical trial landscape for the technology.
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