biorxiv.org· Mortier, J., Scheyltjens, I., Kuznecova, E., Lemeire, K., Parmentier, F., Defauw, A., Vernaillen, F., Persyn, F., De Block, J., Vandamme, N., Dervaux, S., De Rybel, B., Lambrechts, D., Van Hamme, E. ·· 18 hours agoScore50
Navigating the rapidly evolving landscape of sequencing-based spatial transcriptomics technologies: a comprehensive multi-platform benchmark
Navigating the rapidly evolving landscape of sequencing-based spatial transcriptomics technologies: a comprehensive multi-platform benchmark
In brief
A systematic benchmark compares sequencing-based spatial transcriptomics platforms across multiple tissue types and preservation methods, evaluating capture area architecture, capture efficiency, and spatial accuracy under identical conditions. The work also proposes terminology and operational performance metrics for assessing technical performance and its effect on downstream analysis. The results serve as a resource for experimental design and for standardizing future benchmarking.
Source: biorxiv.org · biorxiv.org