medrxiv.org· Lin, D., Zhu, T., Ma, X., Hu, Y., Hao, Y., Cai, Z., Chen, S., Wang, D., Li, M., Chen, X., Li, J., Lin, Y., Huang, H., Yang, Z., Xiao, G., Dai, Z. ·· 2 days agoScore40
Choroid plexus asymmetry on routine MRI as an imaging signature of breast cancer brain metastasis
Choroid plexus asymmetry on routine MRI as an imaging signature of breast cancer brain metastasis
In brief
Choroid plexus asymmetry on routine contrast-enhanced brain MRI is associated with breast cancer brain metastasis. In 1,000 women with breast cancer, 190 with brain metastasis, a deep-learning-derived Choroid Plexus Asymmetry Index was elevated in metastasis cases (median 0.088 vs 0.059; adjusted OR 1.58 per +1 SD, 95% CI 1.32-1.88), independent of peripheral inflammation markers, histological grade, tumour laterality and metastasis side. Total choroid plexus volume did not differ between groups, pointing to asymmetry rather than size as the relevant signature.
Source: medrxiv.org · medrxiv.org