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nature.com· Nature Medicine·· 2026-09-10PickScore66

A clinically-oriented foundation model for intraoperative pathology

A clinically-oriented foundation model for intraoperative pathology

In brief

CRISP, a vision-based pathology foundation model trained exclusively on frozen section slides, outperformed current foundation models and showed extensive validation, including a prospective cohort, for supporting treatment decisions across the surgical workflow. It brings intraoperative pathology decision support closer to clinical use.

Why it matters

Foundation model built solely on frozen sections and validated prospectively for intraoperative treatment decisions.

Source: nature.com · nature.com

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