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#方法/工具

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  1. JAMA57

    Gastric Residual Volume Assessment in Critically Ill Children: The GASTRIC-PICU Randomized Clinical Trial.

    Not routinely assessing gastric residual volume in ventilated critically ill children was noninferior to 6-hourly assessments for survival and ventilator-free days at 30 days (median 25 days in both groups; adjusted OR 0.95 [95% CI 0.86-1.05]). In the trial of 4700 children in pediatric intensive care units in the UK and Switzerland, dropping routine GRV checks also improved feeding: mean energy requirements achieved by 72 hours were 80.3% versus 76.8% (adjusted mean difference 3.2 percentage points, P < .001).

    Why it matters: A large randomized noninferiority trial shows routine GRV checks can be dropped in PICU enteral feeding without harming outcomes.

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